During bone remodeling, which cell type is responsible for bone resorption?

During bone remodeling, which cell type is responsible for bone resorption?

• A. Osteoclast
• B. Osteoblast
• C. Osteocyte
• D. Chondrocyte

Answer: (A)

During bone remodeling, resorption is carried out by osteoclasts, specialized multinucleated cells that attach to the bone surface and create a sealed resorption zone. They secrete acid and proteolytic enzymes that dissolve mineral and degrade the organic matrix, forming resorption pits known as Howship's lacunae. After resorption, osteoblasts come in to lay down new osteoid that mineralizes into bone, while osteocytes are mature bone cells that maintain the matrix and sense mechanical load, and chondrocytes produce cartilage. So, the cell type responsible for bone resorption is the osteoclast.

During bone remodeling, resorption is carried out by osteoclasts, specialized multinucleated cells that attach to the bone surface and create a sealed resorption zone. They secrete acid and proteolytic enzymes that dissolve mineral and degrade the organic matrix, forming resorption pits known as Howship's lacunae. After resorption, osteoblasts come in to lay down new osteoid that mineralizes into bone, while osteocytes are mature bone cells that maintain the matrix and sense mechanical load, and chondrocytes produce cartilage. So, the cell type responsible for bone resorption is the osteoclast.